STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE96133.1UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. (239 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
    
 0.748
AEE96134.1
Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937.
       0.670
AEE96135.1
COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC.
       0.665
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
      0.646
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.574
AEE96250.1
Radical SAM domain protein; COGs: COG1243 Histone acetyltransferase; InterPro IPR007197: IPR006638; KEGG: tte:TTE1468 RNA polymerase II complex ELP3 subunit; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetyltransferase domain (Only BioB/LipA-like domain in Thermotoga); PFAM: Radical SAM superfamily.
  
 
 0.560
AEE96136.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family.
       0.558
AEE96138.1
AAA ATPase central domain protein; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: eel:EUBELI_01348 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase related to the helicase subunit of the Holliday junction resolvase; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus.
       0.524
AEE97979.1
Peptidase U32; COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: tjr:TherJR_1866 peptidase U32; PFAM: peptidase U32; SPTR: Peptidase U32; PFAM: Collagenase; Peptidase family U32.
  
     0.515
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterPro IPR004516: IPR002314: IPR004154: IPR006195: IPR 015807; KEGG: tmt:Tmath_1086 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
  
    0.493
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.