| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE96133.1 | AEE96134.1 | Mahau_0935 | Mahau_0936 | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | 0.670 |
| AEE96133.1 | AEE96135.1 | Mahau_0935 | Mahau_0937 | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | 0.665 |
| AEE96133.1 | AEE96136.1 | Mahau_0935 | Mahau_0938 | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | 0.558 |
| AEE96134.1 | AEE96133.1 | Mahau_0936 | Mahau_0935 | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | 0.670 |
| AEE96134.1 | AEE96135.1 | Mahau_0936 | Mahau_0937 | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | 0.828 |
| AEE96134.1 | AEE96136.1 | Mahau_0936 | Mahau_0938 | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | 0.794 |
| AEE96134.1 | glyA | Mahau_0936 | Mahau_0939 | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.515 |
| AEE96135.1 | AEE96133.1 | Mahau_0937 | Mahau_0935 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | 0.665 |
| AEE96135.1 | AEE96134.1 | Mahau_0937 | Mahau_0936 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | 0.828 |
| AEE96135.1 | AEE96136.1 | Mahau_0937 | Mahau_0938 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | 0.787 |
| AEE96135.1 | glyA | Mahau_0937 | Mahau_0939 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.532 |
| AEE96135.1 | rnfA | Mahau_0937 | Mahau_1157 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.584 |
| AEE96135.1 | rnfB | Mahau_0937 | Mahau_1158 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. | 0.755 |
| AEE96135.1 | rnfC | Mahau_0937 | Mahau_1153 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. | 0.524 |
| AEE96135.1 | rnfD | Mahau_0937 | Mahau_1154 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.630 |
| AEE96135.1 | rnfE | Mahau_0937 | Mahau_1156 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.597 |
| AEE96135.1 | rnfG | Mahau_0937 | Mahau_1155 | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.728 |
| AEE96136.1 | AEE96133.1 | Mahau_0938 | Mahau_0935 | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: cac:CA_C0908 molybdopterin/thiamine biosynthesis family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. | 0.558 |
| AEE96136.1 | AEE96134.1 | Mahau_0938 | Mahau_0936 | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: tpd:Teth39_1038 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. | 0.794 |
| AEE96136.1 | AEE96135.1 | Mahau_0938 | Mahau_0937 | Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family. | COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: aoe:Clos_1706 positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Positive regulator of sigma E, RseC/MucC; PFAM: Positive regulator of sigma(E), RseC/MucC. | 0.787 |