STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEE96138.1AAA ATPase central domain protein; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: eel:EUBELI_01348 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: ATPase related to the helicase subunit of the Holliday junction resolvase; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus. (444 aa)    
Predicted Functional Partners:
AEE97187.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR018329: IPR011545: IPR001650: IPR014021: IPR 014001; KEGG: caa:Caka_2440 ATP-dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family.
 
 
 0.857
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.807
AEE96143.1
DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543: IPR018541: IPR003593; KEGG: cth:Cthe_1095 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: Cell divisionFtsK/SpoIIIE; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
 0.765
AEE95226.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.757
AEE97611.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.757
AEE95378.1
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.
 
      0.711
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.680
AEE96139.1
KEGG: cth:Cthe_0420 dipicolinate synthase subunit A; SPTR: Dipicolinate synthase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; TIGRFAM: dipicolinic acid synthetase, A subunit.
       0.576
AEE96140.1
Dipicolinic acid synthetase, B subunit; InterPro IPR003382: IPR014214; KEGG: drm:Dred_1942 dipicolinate synthase subunit B; PFAM: flavoprotein; SPTR: Flavoprotein; TIGRFAM: dipicolinic acid synthetase, B subunit; PFAM: Flavoprotein; TIGRFAM: dipicolinic acid synthetase, B subunit.
       0.576
AEE96136.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766: IPR017937: IPR017936: IPR005746: IPR 006662; KEGG: ate:Athe_1625 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; protein disulfide-isomerase domain; Belongs to the thioredoxin family.
 
     0.564
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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