STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE96152.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (1112 aa)    
Predicted Functional Partners:
AEE97401.1
Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin.
  
 0.996
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.934
tmk-2
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.934
tmk-3
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.934
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.933
AEE97920.1
InterPro IPR005243; KEGG: dae:Dtox_4282 redox-active disulfide protein 2; SPTR: Redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
  
 
 0.925
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR000623: IPR011994; KEGG: cth:Cthe_0712 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase.
  
 
 0.921
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.915
AEE96591.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR015794: IPR008279: IPR018209: IPR 001697; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.915
AEE96128.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.904
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.