node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEE96176.1 | AEE96179.1 | Mahau_0978 | Mahau_0981 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.866 |
AEE96176.1 | AEE96184.1 | Mahau_0978 | Mahau_0986 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.832 |
AEE96176.1 | fmt | Mahau_0978 | Mahau_0984 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.834 |
AEE96176.1 | gmk | Mahau_0978 | Mahau_0979 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.963 |
AEE96176.1 | priA | Mahau_0978 | Mahau_0982 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.863 |
AEE96176.1 | rlmN | Mahau_0978 | Mahau_0987 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.817 |
AEE96176.1 | rpoZ | Mahau_0978 | Mahau_0980 | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.887 |
AEE96179.1 | AEE96176.1 | Mahau_0981 | Mahau_0978 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | 0.866 |
AEE96179.1 | AEE96184.1 | Mahau_0981 | Mahau_0986 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.866 |
AEE96179.1 | coaD | Mahau_0981 | Mahau_0999 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.946 |
AEE96179.1 | coaX | Mahau_0981 | Mahau_1462 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.957 |
AEE96179.1 | fmt | Mahau_0981 | Mahau_0984 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.857 |
AEE96179.1 | gmk | Mahau_0981 | Mahau_0979 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.932 |
AEE96179.1 | metK | Mahau_0981 | Mahau_1832 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.867 |
AEE96179.1 | priA | Mahau_0981 | Mahau_0982 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.933 |
AEE96179.1 | rlmN | Mahau_0981 | Mahau_0987 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.847 |
AEE96179.1 | rpoZ | Mahau_0981 | Mahau_0980 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.882 |
AEE96184.1 | AEE96176.1 | Mahau_0986 | Mahau_0978 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: cpr:CPR_1720 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family. | 0.832 |
AEE96184.1 | AEE96179.1 | Mahau_0986 | Mahau_0981 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.866 |
AEE96184.1 | coaD | Mahau_0986 | Mahau_0999 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.442 |