Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
tmcALProtein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (408 aa)    
Predicted Functional Partners:
AEE97384.1
RNA methylase; COGs: COG4123 O-methyltransferase; InterPro IPR000241: IPR002052; KEGG: cth:Cthe_2102 methyltransferase small; PFAM: RNA methylase; SPTR: Predicted O-methyltransferase; manually curated; PFAM: Methyltransferase small domain; Belongs to the methyltransferase superfamily.
 
     0.757
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.652
AEE96199.1
Sporulation integral membrane protein YlbJ; COGs: COG3314 conserved hypothetical protein; InterPro IPR011642: IPR014226; KEGG: tpd:Teth39_1298 nucleoside recognition domain-containing protein; PFAM: nucleoside recognition domain protein; SPTR: Sporulation integral membrane protein YlbJ; TIGRFAM: sporulation integral membrane protein YlbJ; PFAM: Nucleoside recognition; TIGRFAM: sporulation integral membrane protein YlbJ.
  
    0.641
AEE96557.1
Methyltransferase type 11; InterPro IPR013216; KEGG: lla:L28696 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 12; PFAM: Methyltransferase domain.
  
    0.621
AEE95911.1
Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR003607: IPR005249: IPR006674; KEGG: tte:TTE0919 HD superfamily hydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: putative HD superfamily hydrolase of NAD metabolism; uncharacterized domain HDIG.
 
  
 0.587
AEE96201.1
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703: IPR003593; KEGG: cce:Ccel_2538 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: ATPase associated with various cellular activities AAA_3; PFAM: ATPase family associated with various cellular activities (AAA).
       0.546
AEE96202.1
Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: ate:Athe_0449 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58.
       0.522
AEE96203.1
KEGG: gym:GYMC10_4008 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.522
AEE97762.1
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.522
AEE97136.1
Methyltransferase type 11; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: cth:Cthe_1959 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain.
  
    0.485
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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