Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE96214.1Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tpd:Teth39_1443 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23; PFAM: Peptidase family M23. (276 aa)    
Predicted Functional Partners:
AEE96215.1
Peptidase M50; InterPro IPR008915: IPR000644; KEGG: pth:PTH_0826 Zn-dependent protease; PFAM: peptidase M50; CBS domain containing protein; SPTR: Peptidase M50; PFAM: CBS domain; Peptidase family M50.
  
  
 0.815
AEE96217.1
Protein of unknown function DUF2344; COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: tpd:Teth39_1440 hypothetical protein; PFAM: Protein of unknown function DUF2344; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344).
       0.707
AEE96216.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197: IPR006638; KEGG: cth:Cthe_0156 radical SAM family protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM; PFAM: Radical SAM superfamily.
       0.706
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.616
AEE96658.1
COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258: IPR000189; KEGG: cce:Ccel_0815 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain.
 
     0.595
AEE96371.1
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460: IPR011816; KEGG: tmt:Tmath_0351 penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
     0.577
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
     
 0.542
AEE95589.1
SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486: IPR013693: IPR013247: IPR003646; KEGG: bld:BLi03809 hypothetical protein; PFAM: Stage II sporulation protein D; SH3 type 3 domain protein; SMART: SH3 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; Bacterial SH3 domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; SpoIID/LytB domain.
 
  
 0.509
AEE96218.1
COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: drm:Dred_0185 CarD family transcriptional regulator; PFAM: transcription factor CarD; SPTR: Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain.
       0.446
AEE96003.1
SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486: IPR013693; KEGG: tte:TTE2451 sporulation protein and related proteins; PFAM: Stage II sporulation protein D; SPTR: Sporulation protein and related proteins; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain.
 
  
 0.441
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.