STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEE96479.1Beta-lactamase domain protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: slp:Slip_1479 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily. (302 aa)    
Predicted Functional Partners:
AEE96481.1
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR019554: IPR000445: IPR003583: IPR004509; KEGG: tpd:Teth39_1421 helix-hairpin-helix repeat-containing competence protein ComEA; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Helix-hairpin-helix motif; SLBB domain; TIGRFAM: competence protein Com [...]
 
  
 0.846
AEE96480.1
DNA-3-methyladenine glycosylase III; COGs: COG2231 Uncharacterized protein related to Endonuclease III; InterPro IPR003265; KEGG: mta:Moth_1560 DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: DNA-3-methyladenine glycosylase III; PFAM: HhH-GPD superfamily base excision DNA repair protein.
       0.773
AEE96478.1
GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterPro IPR000795: IPR004161: IPR000640: IPR005225: IPR 006298; KEGG: tit:Thit_0818 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding prot [...]
       0.689
AEE96477.1
Protein of unknown function DUF988; COGs: COG4708 membrane protein; InterPro IPR010387; KEGG: tex:Teth514_1496 hypothetical protein; PFAM: protein of unknown function DUF988; SPTR: Putative uncharacterized protein; PFAM: QueT transporter.
 
     0.688
rnj
RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
       0.644
AEE96476.1
COGs: COG3679 conserved hypothetical protein; KEGG: sth:STH1710 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF964); Belongs to the UPF0342 family.
       0.644
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.598
AEE95470.1
CMP/dCMP deaminase zinc-binding protein; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125: IPR016192: IPR016473; KEGG: chy:CHY_2556 putative ComE operon protein 2; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Putative comE operon protein 2; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region.
 
    0.537
AEE95434.1
KEGG: tex:Teth514_0744 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3006).
 
     0.509
AEE96474.1
Glucan 1,4-alpha-glucosidase; COGs: COG3387 Glucoamylase and related glycosyl hydrolase; InterPro IPR015220: IPR011613: IPR006425; KEGG: tte:TTE1813 hypothetical protein; PFAM: Glucodextranase N; glycoside hydrolase 15-related; PRIAM: Glucan 1,4-alpha-glucosidase; SPTR: Putative uncharacterized protein; TIGRFAM: glucan 1,4-alpha-glucosidase; PFAM: Glucodextranase, domain N; Glycosyl hydrolases family 15; TIGRFAM: glucan 1,4-alpha-glucosidase.
       0.462
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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