STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE96558.1COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: cth:Cthe_2578 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: Ppx/GppA phosphatase; PFAM: HD domain; Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase. (502 aa)    
Predicted Functional Partners:
AEE96128.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.923
AEE96557.1
Methyltransferase type 11; InterPro IPR013216; KEGG: lla:L28696 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 12; PFAM: Methyltransferase domain.
  
    0.777
tmk-2
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.759
tmk-3
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.723
AEE96561.1
Calcium-translocating P-type ATPase, PMCA-type; COGs: COG0474 Cation transport ATPase; InterPro IPR004014: IPR008250: IPR005834: IPR006068: IPR 001757: IPR000695: IPR018303: IPR006408; KEGG: tte:TTE0030 cation transport ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: calcium-translocating P-type ATPase, PMCA-type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-term [...]
       0.697
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.617
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
    0.614
AEE96661.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000644: IPR000160; KEGG: cbe:Cbei_3303 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.582
AEE96562.1
KEGG: nth:Nther_0553 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.579
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.550
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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