STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE97044.1DNA polymerase III catalytic subunit, DnaE type; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004805: IPR004013: IPR011708: IPR004365: IPR 003141; KEGG: tte:TTE1818 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-dir [...] (1160 aa)    
Predicted Functional Partners:
AEE95882.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790: IPR010372; KEGG: tjr:TherJR_2462 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: DNA-directed DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 0.990
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.988
AEE95585.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: aoe:Clos_0062 DNA polymerase III, delta prime subunit; SPTR: DNA polymerase III, delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau.
  
 0.985
AEE95226.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.984
AEE97611.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.984
AEE95324.1
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR006055: IPR006054: IPR013520; KEGG: ctc:CTC01271 DNA polymerase III PolC; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: DNA polymerase III polC-type; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
    
 0.914
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
0.914
AEE98056.1
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR013520: IPR006055: IPR006054; KEGG: ckr:CKR_P20 DNA polymerase III subunit epsilon; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
    
 0.914
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
       0.854
AEE97047.1
Hypothetical protein; Displays ATPase and GTPase activities.
       0.854
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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