Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE97136.1Methyltransferase type 11; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: cth:Cthe_1959 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. (248 aa)    
Predicted Functional Partners:
AEE97051.1
ABC-1 domain-containing protein; COGs: COG0661 unusual protein kinase; InterPro IPR004147: IPR002114; KEGG: mbu:Mbur_1648 2-octaprenylphenol hydroxylase; PFAM: ABC-1 domain-containing protein; SPTR: ABC1 family protein; PFAM: Lipopolysaccharide core biosynthesis protein (WaaY); ABC1 family; TIGRFAM: 2-polyprenylphenol 6-hydroxylase.
   
 
 0.733
AEE97137.1
Glycosyltransferase 36; COGs: COG3459 Cellobiose phosphorylase; InterPro IPR009342: IPR010383: IPR010403; KEGG: chl:Chy400_4165 glycosyltransferase 36; PFAM: glycosyltransferase 36; carbohydrate binding; glycosyltransferase 36 associated; SPTR: Glycosyltransferase 36; PFAM: Glycosyltransferase family 36; Putative carbohydrate binding domain; Glycosyltransferase 36 associated family.
       0.661
AEE97138.1
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843: IPR001761; KEGG: gym:GYMC10_3167 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI-family regulatory protein; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family.
       0.616
AEE97135.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: tau:Tola_0048 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Kinase, PfkB family; PFAM: pfkB family carbohydrate kinase.
  
    0.608
ispDF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
 
 0.558
AEE97139.1
Extracellular solute-binding protein family 1; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1293 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.
       0.487
AEE95260.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...]
  
 
 0.486
tmcAL
Protein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
    0.485
AEE97102.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173: IPR001440: IPR019734: IPR013026: IPR 001969; KEGG: clj:CLJU_c04550 putative glycosyltransferase; PFAM: glycosyl transferase family 2; Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Tetratricopeptide repeat; Glycosyl transferase family 2.
  
  
 0.456
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.455
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.