Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEE97350.1COGs: COG4747 ACT domain-containing protein; InterPro IPR002912; KEGG: cth:Cthe_0616 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: ACT domain protein; PFAM: ACT domain. (143 aa)    
Predicted Functional Partners:
AEE97351.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
   0.937
AEE97354.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
   0.790
AEE97349.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.773
AEE97352.1
Indolepyruvate ferredoxin oxidoreductase, beta subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752: IPR017719; KEGG: cth:Cthe_0614 indolepyruvate oxidoreductase subunit beta; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, beta subunit.
 
    0.772
AEE97353.1
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
    0.738
AEE97348.1
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: chy:CHY_0730 5-formyltetrahydrofolate cyclo-ligase family protein; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase family protein; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
       0.621
AEE97788.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
   0.608
AEE97355.1
Na+/solute symporter; COGs: COG4145 Na+/panthothenate symporter; InterPro IPR001734; KEGG: mvo:Mvol_1550 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.572
thyX
Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.543
AEE97790.1
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
    0.534
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.