| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE95260.1 | AEE95699.1 | Mahau_0037 | Mahau_0486 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | 0.737 |
| AEE95260.1 | AEE96433.1 | Mahau_0037 | Mahau_1239 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.642 |
| AEE95260.1 | AEE97401.1 | Mahau_0037 | Mahau_2230 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.695 |
| AEE95260.1 | AEE97484.1 | Mahau_0037 | Mahau_2317 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: eat:EAT1b_1024 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nuc [...] | 0.880 |
| AEE95260.1 | guaB | Mahau_0037 | Mahau_1974 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.646 |
| AEE95260.1 | nadE | Mahau_0037 | Mahau_0449 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.602 |
| AEE95699.1 | AEE95260.1 | Mahau_0486 | Mahau_0037 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | 0.737 |
| AEE95699.1 | AEE97401.1 | Mahau_0486 | Mahau_2230 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.432 |
| AEE95699.1 | AEE97484.1 | Mahau_0486 | Mahau_2317 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: eat:EAT1b_1024 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nuc [...] | 0.610 |
| AEE95699.1 | guaB | Mahau_0486 | Mahau_1974 | 1-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.524 |
| AEE96152.1 | AEE97401.1 | Mahau_0954 | Mahau_2230 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.996 |
| AEE96152.1 | nadE | Mahau_0954 | Mahau_0449 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.432 |
| AEE96433.1 | AEE95260.1 | Mahau_1239 | Mahau_0037 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099: IPR001455: IPR 003787; KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SirA-like domain-containing protein; DsrE family protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucle [...] | 0.642 |
| AEE96433.1 | AEE97401.1 | Mahau_1239 | Mahau_2230 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.523 |
| AEE96433.1 | AEE97484.1 | Mahau_1239 | Mahau_2317 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: eat:EAT1b_1024 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nuc [...] | 0.521 |
| AEE96433.1 | nadE | Mahau_1239 | Mahau_0449 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR003754: IPR003043: IPR006366; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.773 |
| AEE97399.1 | AEE97400.1 | Mahau_2228 | Mahau_2229 | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hor:Hore_11260 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | Rubredoxin-type Fe(Cys)4 protein; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR004039; KEGG: mtp:Mthe_0907 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin-type Fe(Cys)4 protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain. | 0.536 |
| AEE97399.1 | AEE97401.1 | Mahau_2228 | Mahau_2230 | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hor:Hore_11260 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.542 |
| AEE97400.1 | AEE97399.1 | Mahau_2229 | Mahau_2228 | Rubredoxin-type Fe(Cys)4 protein; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR004039; KEGG: mtp:Mthe_0907 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin-type Fe(Cys)4 protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain. | Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hor:Hore_11260 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold. | 0.536 |
| AEE97400.1 | AEE97401.1 | Mahau_2229 | Mahau_2230 | Rubredoxin-type Fe(Cys)4 protein; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR004039; KEGG: mtp:Mthe_0907 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin-type Fe(Cys)4 protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain. | Glutaredoxin; InterPro IPR002109; KEGG: mem:Memar_2455 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin. | 0.968 |