| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEE95628.1 | AEE97417.1 | Mahau_0412 | Mahau_2246 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | 0.978 |
| AEE95628.1 | AEE97418.1 | Mahau_0412 | Mahau_2247 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain. | 0.927 |
| AEE95628.1 | carA | Mahau_0412 | Mahau_1551 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR001317: IPR011702: IPR006220: IPR017926: IPR 002474: IPR000991: IPR006274; KEGG: cce:Ccel_2913 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.819 |
| AEE95628.1 | pyrB | Mahau_0412 | Mahau_1424 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132: IPR006131: IPR002082: IPR006130; KEGG: cce:Ccel_0612 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; aspar [...] | 0.794 |
| AEE95628.1 | pyrC | Mahau_0412 | Mahau_1423 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.995 |
| AEE95628.1 | pyrD | Mahau_0412 | Mahau_1419 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.929 |
| AEE95628.1 | pyrE | Mahau_0412 | Mahau_1418 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.979 |
| AEE95628.1 | pyrF | Mahau_0412 | Mahau_1422 | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754: IPR018089: IPR011995; KEGG: cth:Cthe_0951 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.835 |
| AEE97416.1 | AEE97417.1 | Mahau_2245 | Mahau_2246 | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | 0.836 |
| AEE97416.1 | AEE97418.1 | Mahau_2245 | Mahau_2247 | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain. | 0.836 |
| AEE97416.1 | AEE97419.1 | Mahau_2245 | Mahau_2248 | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | Protein of unknown function DUF322; InterPro IPR005531; KEGG: tte:TTE0565 hypothetical protein; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322). | 0.729 |
| AEE97416.1 | pyrB | Mahau_2245 | Mahau_1424 | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132: IPR006131: IPR002082: IPR006130; KEGG: cce:Ccel_0612 aspartate carbamoyltransferase catalytic subunit; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; aspar [...] | 0.451 |
| AEE97417.1 | AEE95628.1 | Mahau_2246 | Mahau_0412 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | 0.978 |
| AEE97417.1 | AEE97416.1 | Mahau_2246 | Mahau_2245 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | 0.836 |
| AEE97417.1 | AEE97418.1 | Mahau_2246 | Mahau_2247 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain. | 0.999 |
| AEE97417.1 | AEE97419.1 | Mahau_2246 | Mahau_2248 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | Protein of unknown function DUF322; InterPro IPR005531; KEGG: tte:TTE0565 hypothetical protein; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322). | 0.722 |
| AEE97417.1 | carA | Mahau_2246 | Mahau_1551 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR001317: IPR011702: IPR006220: IPR017926: IPR 002474: IPR000991: IPR006274; KEGG: cce:Ccel_2913 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.905 |
| AEE97417.1 | pyrD | Mahau_2246 | Mahau_1419 | Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006004; KEGG: tpd:Teth39_0216 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial; glutamate synthase (NADPH), homotetrameric. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.945 |
| AEE97418.1 | AEE95628.1 | Mahau_2247 | Mahau_0412 | Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain. | COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR017900: IPR012135: IPR017896; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily; PFAM: dihydroorotate oxidase; SPTR: Dihydroorotate dehydrogenase superfamily; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein. | 0.927 |
| AEE97418.1 | AEE97416.1 | Mahau_2247 | Mahau_2245 | Sulfide dehydrogenase (flavoprotein) subunit SudB; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR001433: IPR019480: IPR017927: IPR012165; KEGG: cth:Cthe_0373 ferredoxin-NADP(+) reductase subunit alpha; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain. | COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR012904: IPR003265; KEGG: cac:CA_C2707 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: 8-oxoguanine-DNA-glycosylase; PFAM: 8-oxoguanine DNA glycosylase, N-terminal domain; HhH-GPD superfamily base excision DNA repair protein; TIGRFAM: 8-oxoguanine DNA-glycosylase (ogg). | 0.836 |