STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE97538.1Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR003660: IPR000160; KEGG: drm:Dred_0651 diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: HAMP domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (560 aa)    
Predicted Functional Partners:
AEE96661.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000644: IPR000160; KEGG: cbe:Cbei_3303 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 0.938
AEE95944.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: tte:TTE1633 response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
  
 0.919
AEE97552.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: tjr:TherJR_0515 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain.
 
 0.863
AEE96884.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607: IPR006674: IPR006675; KEGG: cth:Cthe_0898 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 0.842
AEE96603.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674: IPR003607; KEGG: tjr:TherJR_0746 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
 
 0.800
AEE97537.1
Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; KEGG: tte:TTE0286 periplasmic sugar-binding proteins; SPTR: Periplasmic sugar-binding proteins; PFAM: family.
     
 0.712
AEE97093.1
Diguanylate cyclase with GAF sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR003018; KEGG: cth:Cthe_1282 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
0.709
AEE97534.1
Xylose-binding protein; COGs: COG4213 ABC-type xylose transport system periplasmic component; KEGG: tmt:Tmath_0328 monosaccharide-transporting ATPase; SPTR: Periplasmic binding protein/LacI family transcriptional regulator; PFAM: family; TIGRFAM: D-xylose ABC transporter, substrate-binding protein.
       0.697
AEE97535.1
Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR000005: IPR020449: IPR018060: IPR 018062; KEGG: tex:Teth514_0224 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Response regulator receiver protein; manually curated; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, A [...]
     
 0.697
AEE97536.1
Integral membrane sensor signal transduction histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660: IPR010559: IPR003594: IPR005467; KEGG: tit:Thit_0243 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.697
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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