STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG). (643 aa)    
Predicted Functional Partners:
AEE97873.1
5-deoxyglucuronate isomerase; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: kol:Kole_0990 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; PFAM: KduI/IolB family.
 
 
 0.999
iolE
2-keto-myo-inositol dehydratase; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
 
 
 0.999
AEE97877.1
Myo-inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: hsm:HSM_0435 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Inositol 2-dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
 
  
 0.947
AEE97872.1
Methylmalonate-semialdehyde dehydrogenase (acylating); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR010061; KEGG: str:Sterm_4016 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase.
  
 0.833
AEE97874.1
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: pac:PPA0454 transaldolase; PFAM: Transaldolase; SPTR: Putative uncharacterized protein; PFAM: Transaldolase.
 
     0.818
AEE97442.1
Acetolactate synthase, large subunit; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012001: IPR012000: IPR011766: IPR000399: IPR 012846; KEGG: cth:Cthe_2714 acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; SPTR: Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-termin [...]
  
  
 
0.571
AEE97869.1
COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439; KEGG: cpy:Cphy_3280 ABC-type sugar transport system ATPase component-like protein; SPTR: ABC-type sugar transport system ATPase component-like protein.
  
  
 0.463
AEE97878.1
KEGG: cce:Ccel_1446 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.451
AEE97866.1
Monosaccharide ABC transporter substrate-binding protein, CUT2 family; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: cpy:Cphy_3277 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family.
 
  
 0.443
AEE97501.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590: IPR001670: IPR018211: IPR012079; KEGG: hmo:HM1_2632 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: Aldehyde-alcohol dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.437
Your Current Organism:
Mahella australiensis
NCBI taxonomy Id: 697281
Other names: M. australiensis 50-1 BON, Mahella australiensis 50-1 BON, Mahella australiensis DSM 15567, Mahella australiensis str. 50-1 BON, Mahella australiensis strain 50-1 BON
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