STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW21564.1PFAM: Pentapeptide repeat; KEGG: sno:Snov_0913 pentapeptide repeat protein. (258 aa)    
Predicted Functional Partners:
EGW22869.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; HAMP linker domain; PAS fold-3; PAS fold; Signal transduction response regulator, receiver region; KEGG: PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif; Signal transduction response regulator, receiver region.
  
 0.923
EGW21471.1
Multi-sensor signal transduction multi-kinase; PFAM: ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase-like domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: putative phytochrome sensor protein; SMART: ATP-binding region, ATPase-like; GAF; Serine/threonine-protein kinase domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
    
 0.848
EGW22114.1
Adenylate/guanylate cyclase with Chase sensor; PFAM: CHASE2; Adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: mgm:Mmc1_1858 adenylate/guanylate cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase.
  
  
  0.822
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.819
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.819
EGW20058.1
Lytic transglycosylase catalytic; KEGG: cps:CPS_1998 putative membrane-bound lytic murein transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup.
   
 
 0.783
EGW23228.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-3; PAS fold; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAC motif; PAS; Signal transduction response regulator, receiver region.
   
 0.659
EGW20036.1
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold; PAS fold-3; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: azo:azo2450 putative two-component system sensor protein; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction response regulator, receiver region; PAS; PAC motif.
   
 0.659
EGW21153.1
Domain of unknown function DUF1745; PFAM: FIST domain, N-terminal; FIST C domain; KEGG: vap:Vapar_6102 domain of unknown function DUF1745.
   
    0.587
EGW23571.1
TIGRFAM: Pyruvate kinase; KEGG: nwa:Nwat_0283 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family.
    
  0.556
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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