STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (303 aa)    
Predicted Functional Partners:
EGW22004.1
KEGG: nwa:Nwat_1397 CRISPR-associated protein Cas2; TIGRFAM: CRISPR-associated protein, Cas2; PFAM: CRISPR-associated protein, Cas2.
 
 
 0.999
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.988
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.988
EGW22010.1
KEGG: nwa:Nwat_1401 CSE4 family CRISPR-associated protein; TIGRFAM: CRISPR-associated protein, CT1975; PFAM: CRISPR-associated protein, CT1975.
 
  
 0.933
EGW22008.1
KEGG: nwa:Nwat_1399 CSE3 family CRISPR-associated protein; TIGRFAM: CRISPR-associated protein, CT1974; PFAM: CRISPR-associated protein, CT1974.
 
  
 0.928
EGW22014.1
CRISPR-associated protein, Cse1 family; KEGG: epy:EpC_08080 hypothetical protein; TIGRFAM: CRISPR-associated protein Cse1; PFAM: CRISPR-associated protein Cse1.
 
  
 0.925
EGW22009.1
KEGG: nwa:Nwat_1400 Cas5 family CRISPR-associated protein; TIGRFAM: CRISPR-associated protein, Cas5e-type; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein, Cas5e-type.
 
  
 0.924
ihfA
Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
    
   0.920
EGW22015.1
TIGRFAM: Helicase Cas3, CRISPR-associated, core; CRISPR-associated HD domain; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; KEGG: gsu:GSU1384 hypothetical protein; SMART: DEAD-like helicase, N-terminal.
 
  
 0.890
EGW22459.1
PFAM: Flagellar protein FlaG protein; KEGG: pen:PSEEN3825 flagellin FlaG.
    
   0.777
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.