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cas1 protein (Methylobacter tundripaludum) - STRING interaction network
"cas1" - CRISPR-associated endonuclease Cas1 in Methylobacter tundripaludum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1 ; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (303 aa)    
Predicted Functional Partners:
Mettu_0799
CRISPR-associated protein Cas2 (101 aa)
 
 
  0.999
Mettu_0803
CRISPR-associated protein, Cse3 family (205 aa)
 
   
  0.971
Mettu_0804
CRISPR-associated protein Cas5 family (230 aa)
 
   
  0.948
Mettu_0805
CRISPR-associated protein, Cse4 family (422 aa)
 
   
  0.947
Mettu_0810
CRISPR-associated helicase Cas3 (919 aa)
 
   
  0.938
Mettu_0809
CRISPR-associated protein, Cse1 family (508 aa)
 
          0.858
Mettu_0812
Putative uncharacterized protein (325 aa)
 
          0.606
Mettu_0446
CRISPR-associated endoribonuclease Cas2 ; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (92 aa)
   
   
  0.540
Mettu_0457
CRISPR-associated protein, Crm2 family (634 aa)
   
        0.497
Mettu_0455
CRISPR-associated RAMP protein, Cmr4 family (296 aa)
              0.493
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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