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fabH protein (Methylobacter tundripaludum) - STRING interaction network
"fabH" - 3-oxoacyl-[acyl-carrier-protein] synthase 3 in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabH3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids; Belongs to the FabH family (322 aa)    
Predicted Functional Partners:
Mettu_0822
TIGRFAM- Malonyl CoA-acyl carrier protein transacylase; KEGG- mca-MCA2002 malonyl CoA-acyl carrier protein transacylase; PFAM- Acyl transferase (318 aa)
 
  0.999
plsX
Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (342 aa)
 
 
  0.994
Mettu_0823
KEGG- pat-Patl_2122 3-oxoacyl-(acyl-carrier-protein) reductase; TIGRFAM- 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM- Short-chain dehydrogenase/reductase SDR (242 aa)
 
 
  0.993
Mettu_0825
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (414 aa)
 
 
  0.990
Mettu_0698
KEGG- mca-MCA2879 3-oxoacyl-(acyl-carrier-protein) synthase I; PFAM- Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Belongs to the beta-ketoacyl-ACP synthases family (407 aa)
 
 
  0.970
Mettu_3290
KEGG- pen-PSEEN0348 3-oxoacyl-(acyl carrier protein) synthase I; PFAM- Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; Belongs to the beta-ketoacyl-ACP synthases family (423 aa)
 
 
  0.957
Mettu_3287
KEGG- sbp-Sbal223_0335 3-oxoacyl-(acyl carrier protein) synthase II; PFAM- Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; Belongs to the beta-ketoacyl-ACP synthases family (409 aa)
 
 
  0.955
Mettu_0824
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (76 aa)
 
  0.950
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA; Belongs to the AccD/PCCB family (320 aa)
 
  0.938
Mettu_2635
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (145 aa)
 
  0.935
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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