STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW22483.1Pyruvate dehydrogenase (acetyl-transferring); KEGG: rpx:Rpdx1_1427 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; overlaps another CDS with the same product name. (356 aa)    
Predicted Functional Partners:
EGW21840.1
KEGG: aeh:Mlg_0270 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
 0.999
EGW22201.1
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
EGW22484.1
Pyruvate dehydrogenase (acetyl-transferring); KEGG: rpb:RPB_3808 acetoin dehydrogenase (TPP-dependent) alpha chain; PFAM: Dehydrogenase, E1 component; overlaps another CDS with the same product name.
 0.999
EGW22200.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: nhl:Nhal_0101 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.996
EGW21841.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: mca:MCA3002 pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.995
EGW19726.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: mca:MCA3002 pyruvate dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.995
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.991
EGW22665.1
TIGRFAM: Phosphoribosyl pyrophosphokinase; KEGG: rfr:Rfer_2240 phosphoribosylpyrophosphate synthetase; PFAM: Phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
   
 0.991
EGW21216.1
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
 0.991
EGW21824.1
Dihydrolipoyl dehydrogenase; KEGG: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 0.990
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.