STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW22686.1Hydrogenase maturation protease; TIGRFAM: Peptidase A31, hydrogen uptake protein; KEGG: mca:MCA0113 HoxW protein. (160 aa)    
Predicted Functional Partners:
EGW22687.1
KEGG: mca:MCA0114 NAD-reducing hydrogenase, beta subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.961
EGW22688.1
KEGG: mca:MCA2726 NAD-reducing hydrogenase, delta subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; overlaps another CDS with the same product name.
 
 
 0.944
EGW22689.1
KEGG: mca:MCA2725 NAD-reducing hydrogenase, gamma subunit; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; overlaps another CDS with the same product name.
 
   
 0.887
EGW22690.1
KEGG: mca:MCA2724 NAD-reducing hydrogenase, alpha subunit; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH:ubiquinone oxidoreductase, 24kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
   
 0.837
EGW20340.1
KEGG: rfr:Rfer_1613 selenide, water dikinase; TIGRFAM: Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal; Selenide water dikinase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 
 0.704
EGW22848.1
NADH dehydrogenase; KEGG: nhl:Nhal_0005 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 
 0.637
EGW21162.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mca:MCA2155 sulfide-quinone reductase.
    
 
 0.637
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
   0.598
EGW21835.1
KEGG: dar:Daro_2889 nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase, large subunit.
  
 
 0.596
EGW20986.1
KEGG: rva:Rvan_0965 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.596
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.