node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mettu_2071 | purE | Mettu_2071 | Mettu_2070 | annotation not available | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) | 0.845 |
Mettu_2071 | purK | Mettu_2071 | Mettu_2069 | annotation not available | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) | 0.845 |
Mettu_2658 | guaA | Mettu_2658 | Mettu_1868 | CoA-binding domain protein; PFAM- CoA-binding; GCN5-related N-acetyltransferase; KEGG- gca-Galf_1381 CoA-binding domain-containing protein | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.760 |
Mettu_2658 | purH | Mettu_2658 | Mettu_2626 | CoA-binding domain protein; PFAM- CoA-binding; GCN5-related N-acetyltransferase; KEGG- gca-Galf_1381 CoA-binding domain-containing protein | Bifunctional purine biosynthesis protein PurH; KEGG- maq-Maqu_3450 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme, formylation region; MGS-like; TIGRFAM- AICARFT/IMPCHase bienzyme; HAMAP- Bifunctional purine biosynthesis protein purH; SMART- AICARFT/IMPCHase bienzyme, formylation region | 0.458 |
Mettu_2658 | purK | Mettu_2658 | Mettu_2069 | CoA-binding domain protein; PFAM- CoA-binding; GCN5-related N-acetyltransferase; KEGG- gca-Galf_1381 CoA-binding domain-containing protein | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) | 0.838 |
Mettu_2658 | purL | Mettu_2658 | Mettu_3166 | CoA-binding domain protein; PFAM- CoA-binding; GCN5-related N-acetyltransferase; KEGG- gca-Galf_1381 CoA-binding domain-containing protein | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.487 |
guaA | Mettu_2658 | Mettu_1868 | Mettu_2658 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | CoA-binding domain protein; PFAM- CoA-binding; GCN5-related N-acetyltransferase; KEGG- gca-Galf_1381 CoA-binding domain-containing protein | 0.760 |
guaA | purC | Mettu_1868 | Mettu_1687 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | 0.960 |
guaA | purD | Mettu_1868 | Mettu_2625 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | Phosphoribosylamine--glycine ligase; PFAM- Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM- Phosphoribosylglycinamide synthetase; HAMAP- Phosphoribosylglycinamide synthetase; KEGG- mca-MCA0361 phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.983 |
guaA | purE | Mettu_1868 | Mettu_2070 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) | 0.927 |
guaA | purF | Mettu_1868 | Mettu_0895 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family | 0.960 |
guaA | purH | Mettu_1868 | Mettu_2626 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | Bifunctional purine biosynthesis protein PurH; KEGG- maq-Maqu_3450 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme, formylation region; MGS-like; TIGRFAM- AICARFT/IMPCHase bienzyme; HAMAP- Bifunctional purine biosynthesis protein purH; SMART- AICARFT/IMPCHase bienzyme, formylation region | 0.974 |
guaA | purK | Mettu_1868 | Mettu_2069 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) | 0.837 |
guaA | purL | Mettu_1868 | Mettu_3166 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate | 0.989 |
guaA | purM | Mettu_1868 | Mettu_1198 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | TIGRFAM- Phosphoribosylformylglycinamidine cyclo-ligase; KEGG- mca-MCA0373 phosphoribosylaminoimidazole synthetase; PFAM- AIR synthase related protein, C-terminal; AIR synthase related protein | 0.912 |
purC | guaA | Mettu_1687 | Mettu_1868 | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP | 0.960 |
purC | purD | Mettu_1687 | Mettu_2625 | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | Phosphoribosylamine--glycine ligase; PFAM- Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM- Phosphoribosylglycinamide synthetase; HAMAP- Phosphoribosylglycinamide synthetase; KEGG- mca-MCA0361 phosphoribosylamine--glycine ligase; Belongs to the GARS family | 0.998 |
purC | purE | Mettu_1687 | Mettu_2070 | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) | 0.994 |
purC | purF | Mettu_1687 | Mettu_0895 | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family | 0.985 |
purC | purH | Mettu_1687 | Mettu_2626 | PFAM- SAICAR synthetase; TIGRFAM- SAICAR synthetase; HAMAP- Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- mca-MCA0021 phosphoribosylaminoimidazole-succinocarboxamide synthase | Bifunctional purine biosynthesis protein PurH; KEGG- maq-Maqu_3450 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme, formylation region; MGS-like; TIGRFAM- AICARFT/IMPCHase bienzyme; HAMAP- Bifunctional purine biosynthesis protein purH; SMART- AICARFT/IMPCHase bienzyme, formylation region | 0.980 |