Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGW23713.1Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (224 aa)    
Predicted Functional Partners:
ccmA
Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 0.999
ccmC
Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
ccmE
Cytochrome c-type biogenesis protein ccmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.996
EGW23716.1
Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
 
 
 0.985
EGW23718.1
KEGG: neu:NE0768 cytochrome c-type biogenesis protein (CcmF); TIGRFAM: Cytochrome c-type biogenesis protein CcmF; PFAM: Cytochrome c assembly protein.
 
  
 0.950
EGW23720.1
Periplasmic protein thiol/disulfide oxidoreductase DsbE; KEGG: eba:ebA3522 cytochrome c biogenesis protein; TIGRFAM: Periplasmic protein thiol:disulphide oxidoreductase DsbE; PFAM: Redoxin.
 
  
 0.917
EGW23722.1
TIGRFAM: Cytochrome c-type biogenesis protein CcmI; KEGG: nhl:Nhal_0849 cytochrome c-type biogenesis protein CcmI.
 
   
 0.905
EGW23721.1
Cytochrome C biogenesis protein; Possible subunit of a heme lyase.
 
   
 0.901
EGW23714.1
KEGG: nmu:Nmul_A2420 hypothetical protein.
       0.620
EGW23719.1
PFAM: Protein of unknown function DUF88; KEGG: cvi:CV_0373 hypothetical protein.
       0.525
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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