STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW23806.1Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: dar:Daro_1132 hypothetical protein. (169 aa)    
Predicted Functional Partners:
EGW22430.1
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
   0.824
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
   0.634
EGW22584.1
UPF0250 protein ybeD; KEGG: tbd:Tbd_0268 hypothetical protein; HAMAP: Protein of unknown function DUF493; PFAM: Protein of unknown function DUF493; Belongs to the UPF0250 family.
    
   0.537
EGW22458.1
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
    0.451
EGW23805.1
Integrase family protein; PFAM: Integrase, catalytic core, phage; Integrase, N-terminal SAM-like, phage; KEGG: pol:Bpro_4806 phage integrase; Belongs to the 'phage' integrase family.
       0.429
EGW22457.1
KEGG: hha:Hhal_0503 flagellar protein FliS; TIGRFAM: Flagellar protein FliS; PFAM: Flagellar protein FliS.
  
  
 0.416
fliA
RNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
  
 0.408
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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