STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW19671.1KEGG: hse:Hsero_2654 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; Cobalamin (vitamin B12) biosynthesis CbiX. (525 aa)    
Predicted Functional Partners:
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
 0.999
EGW19666.1
precorrin-3B C17-methyltransferase; KEGG: hse:Hsero_2649 bifunctional precorrin-3 methyltransferase/precorrin-6x reductase oxidoreductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; Tetrapyrrole methylase.
 
 0.999
EGW19672.1
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: hse:Hsero_2655 precorrin-6y methylase methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase.
 
 
 0.999
EGW19669.1
KEGG: rso:RSp0621 precorrin-2 C20-methyltransferase protein; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; PFAM: Tetrapyrrole methylase.
 
 
 0.998
EGW19667.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; KEGG: ddr:Deide_2p01620 cobalamin biosynthesis protein CbiG.
 
 
 0.997
EGW19668.1
Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; KEGG: hse:Hsero_2651 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase.
 
 
 0.995
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 0.990
EGW19664.1
PFAM: CobB/CobQ-like glutamine amidotransferase; Cobyrinic acid a,c-diamide synthase; KEGG: mca:MCA2290 cobyrinic acid a,c-diamide synthase.
 
 0.989
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.978
EGW19675.1
TIGRFAM: Cobaltochelatase, CobN subunit; KEGG: hse:Hsero_2657 cobalamin biosynthesis protein; PFAM: CobN/magnesium chelatase.
 
  
 0.950
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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