STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lolDLipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (226 aa)    
Predicted Functional Partners:
EGW19884.1
KEGG: mca:MCA2624 lipoprotein ABC transporter, permease protein LolE; TIGRFAM: Lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: Protein of unknown function DUF214, permase predicted.
 0.998
EGW21127.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: rca:Rcas_2537 hypothetical protein.
  
 0.989
EGW21117.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: nhl:Nhal_3357 protein of unknown function DUF214.
 0.984
EGW20597.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: slt:Slit_1490 protein of unknown function DUF214.
 0.980
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
   
 
 0.936
EGW22538.1
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
    
 
 0.876
EGW22352.1
KEGG: amc:MADE_03654 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component.
 
      0.797
macB
Phosphonate-transporting ATPase; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 0.766
fur
Ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; KEGG: mca:MCA2623 ferric uptake regulation protein; Belongs to the Fur family.
     
 0.763
EGW20812.1
PFAM: Protein of unknown function DUF214, permase predicted; KEGG: net:Neut_0973 hypothetical protein.
  
 0.758
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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