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lolD protein (Methylobacter tundripaludum) - STRING interaction network
"lolD" - Lipoprotein-releasing system ATP-binding protein LolD in Methylobacter tundripaludum
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
lolDLipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner (226 aa)    
Predicted Functional Partners:
Mettu_3004
KEGG- mca-MCA2624 lipoprotein ABC transporter, permease protein LolE; TIGRFAM- Lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM- Protein of unknown function DUF214, permase predicted (415 aa)
 
  0.997
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides (651 aa)
 
0.851
Mettu_3743
PFAM- Protein of unknown function DUF214, permase predicted; KEGG- slt-Slit_1490 protein of unknown function DUF214 (407 aa)
  0.805
Mettu_4274
PFAM- Protein of unknown function DUF214, permase predicted; KEGG- nhl-Nhal_3357 protein of unknown function DUF214 (398 aa)
  0.792
fur
PFAM- Ferric-uptake regulator; KEGG- mca-MCA2623 ferric uptake regulation protein; Belongs to the Fur family (139 aa)
              0.788
ftsY
Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components (664 aa)
 
   
  0.774
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (464 aa)
 
   
  0.771
Mettu_4284
PFAM- Protein of unknown function DUF214, permase predicted; KEGG- rca-Rcas_2537 hypothetical protein (804 aa)
 
  0.738
Mettu_4276
KEGG- nhl-Nhal_3354 efflux transporter, RND family, MFP subunit; TIGRFAM- Secretion protein HlyD; PFAM- Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family (381 aa)
   
    0.722
Mettu_3752
KEGG- gpb-HDN1F_29390 HlyD family secretion protein; manually curated; PFAM- Secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family (444 aa)
   
    0.722
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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