node1 | node2 | node1 annotation | node2 annotation | score |
Mettu_0283 | Mettu_0493 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.672 |
Mettu_0283 | Mettu_1414 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit | 0.647 |
Mettu_0283 | Mettu_1818 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit | 0.647 |
Mettu_0283 | Mettu_2509 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | TIGRFAM- Citrate synthase, type II; KEGG- neu-NE2373 citrate synthase; PFAM- Citrate synthase-like; Belongs to the citrate synthase family | 0.854 |
Mettu_0283 | Mettu_2982 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family | 0.701 |
Mettu_0283 | Mettu_3174 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | TIGRFAM- Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG- ank-AnaeK_2235 isocitrate dehydrogenase, NADP-dependent; PFAM- Isocitrate/isopropylmalate dehydrogenase | 0.818 |
Mettu_0283 | Mettu_3175 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | KEGG- mca-MCA3071 isocitrate dehydrogenase, NAD-dependent, putative; PFAM- Isocitrate/isopropylmalate dehydrogenase | 0.907 |
Mettu_0283 | Mettu_3176 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | Aconitate hydratase B; TIGRFAM- Aconitase B, bacterial; KEGG- mca-MCA2485 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; PFAM- Aconitase B, N-terminal, bacterial; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Belongs to the aconitase/IPM isomerase family | 0.778 |
Mettu_0283 | Mettu_3447 | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | TIGRFAM- Citrate synthase, type II; KEGG- dbr-Deba_1491 citrate synthase I; PFAM- Citrate synthase-like; Belongs to the citrate synthase family | 0.854 |
Mettu_0493 | Mettu_0283 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | KEGG- nhl-Nhal_1482 aconitate hydratase; TIGRFAM- Aconitase, putative; PFAM- Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel | 0.672 |
Mettu_0493 | Mettu_0654 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate | 0.672 |
Mettu_0493 | Mettu_1414 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit | 0.961 |
Mettu_0493 | Mettu_1818 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Succinate--CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit | 0.976 |
Mettu_0493 | Mettu_2509 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | TIGRFAM- Citrate synthase, type II; KEGG- neu-NE2373 citrate synthase; PFAM- Citrate synthase-like; Belongs to the citrate synthase family | 0.934 |
Mettu_0493 | Mettu_2982 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family | 0.977 |
Mettu_0493 | Mettu_3174 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | TIGRFAM- Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG- ank-AnaeK_2235 isocitrate dehydrogenase, NADP-dependent; PFAM- Isocitrate/isopropylmalate dehydrogenase | 0.843 |
Mettu_0493 | Mettu_3175 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | KEGG- mca-MCA3071 isocitrate dehydrogenase, NAD-dependent, putative; PFAM- Isocitrate/isopropylmalate dehydrogenase | 0.495 |
Mettu_0493 | Mettu_3176 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | Aconitate hydratase B; TIGRFAM- Aconitase B, bacterial; KEGG- mca-MCA2485 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; PFAM- Aconitase B, N-terminal, bacterial; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Belongs to the aconitase/IPM isomerase family | 0.907 |
Mettu_0493 | Mettu_3447 | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | TIGRFAM- Citrate synthase, type II; KEGG- dbr-Deba_1491 citrate synthase I; PFAM- Citrate synthase-like; Belongs to the citrate synthase family | 0.930 |
Mettu_0654 | Mettu_0493 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate | TIGRFAM- Succinate dehydrogenase, flavoprotein subunit; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; KEGG- mca-MCA1550 succinate dehydrogenase flavoprotein subunit; PFAM- Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily | 0.672 |