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greA protein (Methylobacter tundripaludum) - STRING interaction network
"greA" - Transcript cleavage factor GreA in Methylobacter tundripaludum
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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greATranscript cleavage factor GreA ; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3’terminus. GreA releases sequences of 2 to 3 nucleotides (158 aa)    
Predicted Functional Partners:
rpoC
Transcriptase subunit beta’ ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1397 aa)
       
 
  0.927
Mettu_3208
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) (1072 aa)
     
 
  0.924
rpoA
Transcriptase subunit alpha ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (337 aa)
 
 
 
  0.870
rpoZ
Transcriptase subunit omega ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta’ subunit thereby facilitating its interaction with the beta and alpha subunits (81 aa)
 
 
  0.862
rpoB
Transcriptase subunit beta ; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1364 aa)
   
 
 
  0.825
dksA
RNA polymerase-binding transcription factor DksA ; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (144 aa)
     
 
  0.815
rho
ATP-dependent helicase Rho ; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho’s RNA-dependent ATPase activity, and release of the mRNA from the DNA template (418 aa)
   
 
 
  0.789
murI
Glutamate racemase ; Provides the (R)-glutamate required for cell wall biosynthesis (270 aa)
     
 
  0.764
nusA
Transcription termination/antitermination protein NusA ; Participates in both transcription termination and antitermination (505 aa)
 
     
  0.762
rpoH
RNA polymerase sigma-32 factor ; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes (285 aa)
 
   
  0.718
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum, M. tundripaludum SV96, Methylobacter, Methylobacter sp. SV96, Methylobacter tundripaludum, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum Wartiainen et al. 2006, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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