| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGW20645.1 | EGW22771.1 | Mettu_3793 | Mettu_1595 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | 0.991 |
| EGW20645.1 | argG | Mettu_3793 | Mettu_1221 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: mca:MCA1099 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.866 |
| EGW20645.1 | carA | Mettu_3793 | Mettu_3209 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: mmw:Mmwyl1_4035 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. | 0.992 |
| EGW20645.1 | carB | Mettu_3793 | Mettu_3208 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: mca:MCA1852 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Belongs to the CarB family. | 0.994 |
| EGW20645.1 | purF | Mettu_3793 | Mettu_0895 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
| EGW20645.1 | purL | Mettu_3793 | Mettu_3166 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.926 |
| EGW20645.1 | pyrB | Mettu_3793 | Mettu_1596 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: mca:MCA2333 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.981 |
| EGW20645.1 | pyrE | Mettu_3793 | Mettu_2364 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.974 |
| EGW20645.1 | pyrF | Mettu_3793 | Mettu_1128 | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.978 |
| EGW21988.1 | EGW22771.1 | Mettu_0783 | Mettu_1595 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | 0.942 |
| EGW21988.1 | argG | Mettu_0783 | Mettu_1221 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: mca:MCA1099 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.998 |
| EGW21988.1 | carA | Mettu_0783 | Mettu_3209 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: mmw:Mmwyl1_4035 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. | 0.997 |
| EGW21988.1 | carB | Mettu_0783 | Mettu_3208 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: mca:MCA1852 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Belongs to the CarB family. | 0.997 |
| EGW21988.1 | purF | Mettu_0783 | Mettu_0895 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.538 |
| EGW21988.1 | purL | Mettu_0783 | Mettu_3166 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.450 |
| EGW21988.1 | pyrB | Mettu_0783 | Mettu_1596 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; HAMAP: Aspartate carbamoyltransferase; KEGG: mca:MCA2333 aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.919 |
| EGW22771.1 | EGW20645.1 | Mettu_1595 | Mettu_3793 | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | PFAM: Oxidoreductase FAD/NAD(P)-binding; KEGG: mca:MCA0335 hypothetical protein. | 0.991 |
| EGW22771.1 | EGW21988.1 | Mettu_1595 | Mettu_0783 | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.942 |
| EGW22771.1 | carA | Mettu_1595 | Mettu_3209 | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | TIGRFAM: Carbamoyl phosphate synthase, small subunit; KEGG: mmw:Mmwyl1_4035 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; Belongs to the CarA family. | 0.996 |
| EGW22771.1 | carB | Mettu_1595 | Mettu_3208 | Dihydroorotase, multifunctional complex type; KEGG: mca:MCA2332 dihydroorotase family protein; TIGRFAM: Dihydroorotase multifunctional complex type; PFAM: Amidohydrolase 1. | TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent; KEGG: mca:MCA1852 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; MGS-like; Belongs to the CarB family. | 0.996 |