Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EGW20947.1PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: cyt:cce_3339 hypothetical protein. (202 aa)    
Predicted Functional Partners:
EGW20948.1
KEGG: gmc:GY4MC1_2427 xanthine dehydrogenase; PFAM: XdhC- CoxI.
  
 0.996
EGW20950.1
Isoquinoline 1-oxidoreductase; KEGG: ote:Oter_2803 2Fe-2S iron-sulfur cluster binding domain-containing protein; PFAM: [2Fe-2S]-binding; Ferredoxin.
 
  
 0.885
EGW19753.1
XshC-Cox1-family protein; PFAM: XdhC- CoxI; KEGG: aeh:Mlg_1569 hypothetical protein.
 
  
 0.865
EGW20949.1
KEGG: ote:Oter_2802 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding.
 
   
 0.865
EGW20013.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
   
  0.864
EGW19752.1
KEGG: har:HEAR1179 isoquinoline 1-oxidoreductase alpha subunit; PFAM: [2Fe-2S]-binding; Ferredoxin.
 
  
 0.800
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
    
 0.765
EGW19751.1
KEGG: mno:Mnod_6607 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding.
 
   
 0.702
EGW22558.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; KEGG: chl:Chy400_2186 HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; Belongs to the HAD-like hydrolase superfamily.
 
      0.539
fdhD
Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
  
  
  0.482
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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