STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGW20974.1KEGG: nhl:Nhal_1356 hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like. (220 aa)    
Predicted Functional Partners:
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.992
EGW19737.1
PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; KEGG: mca:MCA1138 hydrogenase subunit.
   
 
 0.977
EGW20971.1
KEGG: rva:Rvan_0978 hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.960
EGW20972.1
KEGG: app:CAP2UW1_0733 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
  
 0.956
EGW20969.1
KEGG: alv:Alvin_2797 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein.
 
  
 0.859
EGW20446.1
Peptidylprolyl isomerase; KEGG: cja:CJA_1627 FKBP-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type.
    
 
 0.846
EGW20968.1
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.844
EGW20975.1
KEGG: ptm:GSPATT00032799001 hypothetical protein.
       0.762
EGW20982.1
KEGG: rva:Rvan_0969 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
  
  
 0.735
EGW21834.1
Cytochrome-c3 hydrogenase; KEGG: lch:Lcho_1349 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit.
 
  
 0.671
Your Current Organism:
Methylobacter tundripaludum
NCBI taxonomy Id: 697282
Other names: M. tundripaludum SV96, Methylobacter sp. SV96, Methylobacter tundripaludum DSM 17260, Methylobacter tundripaludum SV96, Methylobacter tundripaludum str. SV96, Methylobacter tundripaludum strain SV96
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.