STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cnnm4Metal transporter CNNM4. (460 aa)    
Predicted Functional Partners:
GMPS
GMP synthase [glutamine-hydrolyzing].
  
 
 0.906
C0J52_17274
Cyclic nucleotide-binding domain-containing protein.
 
      0.898
C0J52_14852
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.850
ATIC
Bifunctional purine biosynthesis protein PURH.
    
 0.843
Ptp4a1
Protein tyrosine phosphatase type IVA 1.
    
 
 0.815
C0J52_05231
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.805
C0J52_11664
Uncharacterized protein.
  
 
  0.791
C0J52_01149
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.774
Aprt
Adenine phosphoribosyltransferase.
  
 
 0.762
5NUC
Protein 5NUC; Belongs to the 5'-nucleotidase family.
    
 0.705
Your Current Organism:
Blattella germanica
NCBI taxonomy Id: 6973
Other names: B. germanica, German cockroach
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