STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C0J52_25191E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (255 aa)    
Predicted Functional Partners:
CACYBP
Calcyclin-binding protein.
    
 0.889
C0J52_27953
WD_REPEATS_REGION domain-containing protein.
    
  0.819
ebi
F-box-like/WD repeat-containing protein ebi.
    
  0.819
Tbl1xr1
F-box-like/WD repeat-containing protein TBL1XR1.
    
  0.819
ube2t
Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.654
C0J52_06584
Uncharacterized protein.
    
  0.585
arm
Armadillo segment polarity protein.
    
  0.466
USP5
Ubiquitin carboxyl-terminal hydrolase.
    
  0.464
Your Current Organism:
Blattella germanica
NCBI taxonomy Id: 6973
Other names: B. germanica, German cockroach
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