C0J52_25040 protein (Blattella germanica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

C0J52_25040

Uncharacterized protein. (79 aa)

Predicted Functional Partners:

EED

0.574

C0J52_05918

0.567

C0J52_02156

0.557

GGCT

0.537

h2afv

0.528

ash2

0.500

C0J52_11735

0.499

Caf1

0.499

C0J52_19407

0.473

C0J52_13992

0.447

Your Current Organism:

Blattella germanica

NCBI taxonomy Id: 6973
Other names: B. germanica, German cockroach

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C0J52_02156	C0J52_11735	A0A2P8ZHN7	A0A2P8YDT1	Uncharacterized protein.	Uncharacterized protein.	0.997
C0J52_02156	C0J52_19407	A0A2P8ZHN7	A0A2P8XM66	Uncharacterized protein.	Uncharacterized protein.	0.709
C0J52_02156	C0J52_25040	A0A2P8ZHN7	A0A2P8XNN1	Uncharacterized protein.	Uncharacterized protein.	0.557
C0J52_02156	Caf1	A0A2P8ZHN7	A0A2P8ZKJ6	Uncharacterized protein.	Putative histone-binding protein Caf1.	0.997
C0J52_02156	ash2	A0A2P8ZHN7	A0A2P8YJK8	Uncharacterized protein.	Set1/Ash2 histone methyltransferase complex subunit ASH2.	0.746
C0J52_02156	h2afv	A0A2P8ZHN7	A0A2P8XJ03	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.949
C0J52_05918	C0J52_11735	A0A2P8YWC0	A0A2P8YDT1	VEFS-Box domain-containing protein.	Uncharacterized protein.	0.991
C0J52_05918	C0J52_19407	A0A2P8YWC0	A0A2P8XM66	VEFS-Box domain-containing protein.	Uncharacterized protein.	0.686
C0J52_05918	C0J52_25040	A0A2P8YWC0	A0A2P8XNN1	VEFS-Box domain-containing protein.	Uncharacterized protein.	0.567
C0J52_05918	Caf1	A0A2P8YWC0	A0A2P8ZKJ6	VEFS-Box domain-containing protein.	Putative histone-binding protein Caf1.	0.998
C0J52_05918	EED	A0A2P8YWC0	A0A2P8ZKJ7	VEFS-Box domain-containing protein.	Polycomb protein EED.	0.999
C0J52_05918	GGCT	A0A2P8YWC0	A0A2P8YQ23	VEFS-Box domain-containing protein.	Gamma-glutamylcyclotransferase.	0.822
C0J52_05918	ash2	A0A2P8YWC0	A0A2P8YJK8	VEFS-Box domain-containing protein.	Set1/Ash2 histone methyltransferase complex subunit ASH2.	0.545
C0J52_05918	h2afv	A0A2P8YWC0	A0A2P8XJ03	VEFS-Box domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.744
C0J52_11735	C0J52_02156	A0A2P8YDT1	A0A2P8ZHN7	Uncharacterized protein.	Uncharacterized protein.	0.997
C0J52_11735	C0J52_05918	A0A2P8YDT1	A0A2P8YWC0	Uncharacterized protein.	VEFS-Box domain-containing protein.	0.991
C0J52_11735	C0J52_19407	A0A2P8YDT1	A0A2P8XM66	Uncharacterized protein.	Uncharacterized protein.	0.832
C0J52_11735	C0J52_25040	A0A2P8YDT1	A0A2P8XNN1	Uncharacterized protein.	Uncharacterized protein.	0.499
C0J52_11735	EED	A0A2P8YDT1	A0A2P8ZKJ7	Uncharacterized protein.	Polycomb protein EED.	0.991
C0J52_11735	GGCT	A0A2P8YDT1	A0A2P8YQ23	Uncharacterized protein.	Gamma-glutamylcyclotransferase.	0.856

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.856

expected number of edges:

33

PPI enrichment p-value:

0.959

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2713

Alpha/beta hydrolase fold-1

4 of 6

2.57

3.35

1.13e-06

CL:1085

Phosphopantetheine attachment site, and Thioesterase domain

2 of 10

2.04

0.79

0.0417

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031975

Envelope

4 of 85

1.42

1.1

0.0033

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

3 of 47

1.55

0.9

0.0158

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00561

Alpha/beta hydrolase fold

3 of 22

1.88

1.19

0.0061

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000073

Alpha/beta hydrolase fold-1

4 of 22

2.0

2.04

0.00012

IPR032821

Polyketide synthase, C-terminal extension

3 of 16

2.02

1.4

0.0028

IPR013968

Polyketide synthase, ketoreductase domain

3 of 15

2.04

1.4

0.0028

IPR016036

Malonyl-CoA ACP transacylase, ACP-binding

3 of 17

1.99

1.39

0.0028

IPR014043

Acyl transferase

3 of 17

1.99

1.39

0.0028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

3 of 13

2.11

1.88

0.00034

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

3 of 15

2.04

1.85

0.00034

SM00823

Phosphopantetheine attachment site

3 of 16

2.02

1.84

0.00034

SM00826

PKS_DH

2 of 4

2.44

1.61

0.0016

SM00825

Beta-ketoacyl synthase

2 of 12

1.96

1.16

0.0078

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