C0J52_16796 protein (Blattella germanica) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

C0J52_16796

Uncharacterized protein. (1004 aa)

Predicted Functional Partners:

C0J52_27390

0.857

Cask

0.857

C0J52_21141

0.857

C0J52_07658

0.797

cni

0.797

PICK1

0.729

C0J52_01656

0.700

comt

0.684

GRIP1

0.580

C0J52_12454

0.580

Your Current Organism:

Blattella germanica

NCBI taxonomy Id: 6973
Other names: B. germanica, German cockroach

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C0J52_01656	C0J52_16796	A0A2P8ZEI9	A0A2P8Y9B3	Uncharacterized protein.	Uncharacterized protein.	0.700
C0J52_01656	C0J52_21141	A0A2P8ZEI9	A0A2P8Y5H9	Uncharacterized protein.	L27 domain-containing protein.	0.999
C0J52_01656	C0J52_27390	A0A2P8ZEI9	A0A2P8XRE8	Uncharacterized protein.	PDZ domain-containing protein.	0.999
C0J52_01656	Cask	A0A2P8ZEI9	A0A2P8Y5H2	Uncharacterized protein.	Peripheral plasma membrane protein CASK.	0.999
C0J52_01656	PICK1	A0A2P8ZEI9	A0A2P8YHA5	Uncharacterized protein.	PRKCA-binding protein.	0.598
C0J52_01656	comt	A0A2P8ZEI9	A0A2P8ZDT3	Uncharacterized protein.	Vesicle-fusing ATPase 1; Belongs to the AAA ATPase family.	0.537
C0J52_07658	C0J52_16796	A0A2P8YIL5	A0A2P8Y9B3	Uncharacterized protein.	Uncharacterized protein.	0.797
C0J52_07658	comt	A0A2P8YIL5	A0A2P8ZDT3	Uncharacterized protein.	Vesicle-fusing ATPase 1; Belongs to the AAA ATPase family.	0.707
C0J52_12454	C0J52_16796	A0A2P8Y9I0	A0A2P8Y9B3	Uncharacterized protein.	Uncharacterized protein.	0.580
C0J52_12454	PICK1	A0A2P8Y9I0	A0A2P8YHA5	Uncharacterized protein.	PRKCA-binding protein.	0.681
C0J52_12454	comt	A0A2P8Y9I0	A0A2P8ZDT3	Uncharacterized protein.	Vesicle-fusing ATPase 1; Belongs to the AAA ATPase family.	0.553
C0J52_16796	C0J52_01656	A0A2P8Y9B3	A0A2P8ZEI9	Uncharacterized protein.	Uncharacterized protein.	0.700
C0J52_16796	C0J52_07658	A0A2P8Y9B3	A0A2P8YIL5	Uncharacterized protein.	Uncharacterized protein.	0.797
C0J52_16796	C0J52_12454	A0A2P8Y9B3	A0A2P8Y9I0	Uncharacterized protein.	Uncharacterized protein.	0.580
C0J52_16796	C0J52_21141	A0A2P8Y9B3	A0A2P8Y5H9	Uncharacterized protein.	L27 domain-containing protein.	0.857
C0J52_16796	C0J52_27390	A0A2P8Y9B3	A0A2P8XRE8	Uncharacterized protein.	PDZ domain-containing protein.	0.857
C0J52_16796	Cask	A0A2P8Y9B3	A0A2P8Y5H2	Uncharacterized protein.	Peripheral plasma membrane protein CASK.	0.857
C0J52_16796	GRIP1	A0A2P8Y9B3	A0A2P8Y3U7	Uncharacterized protein.	Glutamate receptor-interacting protein 1.	0.580
C0J52_16796	PICK1	A0A2P8Y9B3	A0A2P8YHA5	Uncharacterized protein.	PRKCA-binding protein.	0.729
C0J52_16796	cni	A0A2P8Y9B3	A0A2P8ZLZ4	Uncharacterized protein.	Protein cornichon.	0.797

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.88

expected number of edges:

13

PPI enrichment p-value:

1.79e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042793

Plastid transcription

5 of 37

3.11

5.83

1.83e-11

GO:0009662

Etioplast organization

4 of 7

3.74

5.7

5.33e-11

GO:0009658

Chloroplast organization

5 of 936

1.71

2.01

2.09e-05

GO:0016310

Phosphorylation

10 of 6395

1.17

1.61

1.21e-08

GO:0009059

Macromolecule biosynthetic process

6 of 5167

1.04

0.83

0.0022

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016301

Kinase activity

10 of 7210

1.12

1.44

6.59e-08

GO:0019200

Carbohydrate kinase activity

2 of 128

2.17

0.77

0.0378

GO:0016773

Phosphotransferase activity, alcohol group as acceptor

6 of 6421

0.95

0.62

0.0126

GO:0003824

Catalytic activity

11 of 41832

0.4

0.29

0.0219

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042644

Chloroplast nucleoid

6 of 80

2.86

6.83

1.07e-13

GO:0000427

Plastid-encoded plastid RNA polymerase complex

4 of 21

3.26

5.33

1.89e-10

GO:0009507

Chloroplast

9 of 7039

1.09

1.33

2.45e-07

GO:0110165

Cellular anatomical entity

11 of 19699

0.73

0.71

1.03e-06

GO:0005737

Cytoplasm

11 of 38115

0.44

0.37

0.00088

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:139517

Plastid-encoded plastid RNA polymerase complex, and Thioredoxin-like protein CITRX, chloroplastic

4 of 25

3.18

4.19

2.37e-08

CL:139520

Plastid-encoded plastid RNA polymerase complex, and Thioredoxin-like protein CITRX, chloroplastic

3 of 20

3.16

3.02

3.32e-06

CL:139521

Plastid-encoded plastid RNA polymerase complex, and Thioredoxin-like protein CITRX, chloroplastic

2 of 13

3.17

1.5

0.0020

CL:107029

Mixed, incl. Synthesis of Dolichyl-phosphate, and Dolichol-linked oligosaccharide biosynthetic process

2 of 49

2.59

0.92

0.0217

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

3 of 635

1.65

1.2

0.0028

map01100

Metabolic pathways

11 of 20556

0.71

0.68

2.53e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-71336

Pentose phosphate pathway

7 of 131

2.71

7.53

1.66e-15

MAP-71387

Metabolism of carbohydrates

8 of 1119

1.83

4.0

1.20e-11

MAP-1430728

Metabolism

11 of 11326

0.97

1.17

6.72e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042646

Plastid nucleoid

6 of 93

2.79

6.46

4.59e-13

GOCC:0042644

Chloroplast nucleoid

5 of 84

2.75

5.28

9.93e-11

GOCC:0009536

Plastid

9 of 5685

1.18

1.57

6.64e-08

GOCC:0110165

Cellular anatomical entity

11 of 8339

1.1

1.53

3.30e-10

GOCC:0009507

Chloroplast

8 of 5048

1.18

1.46

9.84e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0418

Kinase

4 of 2169

1.25

0.73

0.0191

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00294

pfkB family carbohydrate kinase

9 of 54

3.2

12.77

9.89e-25

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR011611

Carbohydrate kinase PfkB

10 of 54

3.25

14.58

3.48e-28

IPR029056

Ribokinase-like

10 of 71

3.13

13.97

2.16e-27

IPR002139

Ribokinase/fructokinase

5 of 20

3.38

6.67

7.23e-13

IPR002173

Carbohydrate/purine kinase, PfkB, conserved site

5 of 36

3.12

6.04

7.64e-12

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