C0J52_15555 protein (Blattella germanica) - STRING interaction network

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Known Interactions

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Predicted Interactions

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gene co-occurrence

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protein homology

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Score

C0J52_15555

Reverse transcriptase domain-containing protein. (829 aa)

Predicted Functional Partners:

C0J52_19556

0.597

C0J52_06071

0.561

GGCT

0.535

brcc3

0.532

C0J52_05687

0.532

C0J52_07190

0.526

RPL21

0.502

C0J52_21737

0.483

RpL13A

0.462

C0J52_16891

0.451

Your Current Organism:

Blattella germanica

NCBI taxonomy Id: 6973
Other names: B. germanica, German cockroach

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C0J52_05687	C0J52_06071	A0A2P8ZG05	A0A2P8Z3V2	MPN domain-containing protein.	Uncharacterized protein.	0.978
C0J52_05687	C0J52_15555	A0A2P8ZG05	A0A2P8YGI5	MPN domain-containing protein.	Reverse transcriptase domain-containing protein.	0.532
C0J52_05687	C0J52_19556	A0A2P8ZG05	A0A2P8Y9B9	MPN domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.896
C0J52_05687	C0J52_21737	A0A2P8ZG05	A0A2P8XL32	MPN domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.577
C0J52_05687	GGCT	A0A2P8ZG05	A0A2P8YQ23	MPN domain-containing protein.	Gamma-glutamylcyclotransferase.	0.977
C0J52_06071	C0J52_05687	A0A2P8Z3V2	A0A2P8ZG05	Uncharacterized protein.	MPN domain-containing protein.	0.978
C0J52_06071	C0J52_15555	A0A2P8Z3V2	A0A2P8YGI5	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.561
C0J52_06071	C0J52_19556	A0A2P8Z3V2	A0A2P8Y9B9	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.977
C0J52_06071	C0J52_21737	A0A2P8Z3V2	A0A2P8XL32	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.720
C0J52_06071	GGCT	A0A2P8Z3V2	A0A2P8YQ23	Uncharacterized protein.	Gamma-glutamylcyclotransferase.	0.638
C0J52_06071	brcc3	A0A2P8Z3V2	A0A2P8YAA1	Uncharacterized protein.	Lys-63-specific deubiquitinase BRCC36.	0.999
C0J52_07190	C0J52_15555	A0A2P8Y954	A0A2P8YGI5	Uncharacterized protein.	Reverse transcriptase domain-containing protein.	0.526
C0J52_07190	C0J52_16891	A0A2P8Y954	A0A2P8XT87	Uncharacterized protein.	Ribosomal_L2 domain-containing protein.	0.489
C0J52_15555	C0J52_05687	A0A2P8YGI5	A0A2P8ZG05	Reverse transcriptase domain-containing protein.	MPN domain-containing protein.	0.532
C0J52_15555	C0J52_06071	A0A2P8YGI5	A0A2P8Z3V2	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.561
C0J52_15555	C0J52_07190	A0A2P8YGI5	A0A2P8Y954	Reverse transcriptase domain-containing protein.	Uncharacterized protein.	0.526
C0J52_15555	C0J52_16891	A0A2P8YGI5	A0A2P8XT87	Reverse transcriptase domain-containing protein.	Ribosomal_L2 domain-containing protein.	0.451
C0J52_15555	C0J52_19556	A0A2P8YGI5	A0A2P8Y9B9	Reverse transcriptase domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.597
C0J52_15555	C0J52_21737	A0A2P8YGI5	A0A2P8XL32	Reverse transcriptase domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.483
C0J52_15555	GGCT	A0A2P8YGI5	A0A2P8YQ23	Reverse transcriptase domain-containing protein.	Gamma-glutamylcyclotransferase.	0.535

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Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.863

expected number of edges:

10

PPI enrichment p-value:

2.66e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006304

DNA modification

4 of 6

2.34

2.55

1.24e-05

GO:0009307

DNA restriction-modification system

3 of 3

2.52

1.92

0.00027

GO:0090304

Nucleic acid metabolic process

6 of 283

0.85

0.58

0.0094

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004386

Helicase activity

3 of 25

1.6

0.67

0.0471

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1905347

Endodeoxyribonuclease complex

2 of 6

2.04

0.8

0.0321

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7030

Mixed, incl. DNA modification, and YgjP-like, metallopeptidase domain

8 of 17

2.19

5.76

6.41e-14

CL:7033

Mixed, incl. DNA modification, and Integrase, catalytic core

7 of 11

2.32

5.6

1.29e-12

CL:6963

Mostly uncharacterized, incl. DNA modification, and Helicase activity

10 of 52

1.8

4.58

6.23e-15

CL:7036

DNA restriction-modification system, and DNA alkylation

5 of 5

2.52

4.35

3.62e-09

CL:6962

Mixed, incl. DNA metabolic process, and Helicase activity

11 of 95

1.58

3.58

6.23e-15

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0019812

Type I site-specific deoxyribonuclease complex

2 of 2

2.52

1.0

0.0151

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0175

Coiled coil

6 of 249

0.9

0.63

0.0082

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13749

Putative ATP-dependent DNA helicase recG C-terminal

2 of 2

2.52

0.86

0.0273

PF04326

Putative DNA-binding domain

2 of 2

2.52

0.86

0.0273

PF13304

AAA domain, putative AbiEii toxin, Type IV TA system

2 of 4

2.22

0.85

0.0273

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