| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEM77542.1 | AEM77543.1 | Thewi_0026 | Thewi_0027 | KEGG: tbo:Thebr_0027 hypothetical protein. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.529 |
| AEM77543.1 | AEM77542.1 | Thewi_0027 | Thewi_0026 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | KEGG: tbo:Thebr_0027 hypothetical protein. | 0.529 |
| AEM77543.1 | AEM78779.1 | Thewi_0027 | Thewi_1357 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: tbo:Thebr_1246 membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | 0.622 |
| AEM77543.1 | AEM79494.1 | Thewi_0027 | Thewi_2144 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | 0.724 |
| AEM77543.1 | atpE | Thewi_0027 | Thewi_0746 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.494 |
| AEM77543.1 | ffh | Thewi_0027 | Thewi_1417 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.514 |
| AEM77543.1 | lepA | Thewi_0027 | Thewi_1039 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.715 |
| AEM77543.1 | minE | Thewi_0027 | Thewi_0990 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.629 |
| AEM77543.1 | rimM | Thewi_0027 | Thewi_1414 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.503 |
| AEM77543.1 | rnhB | Thewi_0027 | Thewi_1406 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.627 |
| AEM77543.1 | topA | Thewi_0027 | Thewi_1404 | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.581 |
| AEM78779.1 | AEM77543.1 | Thewi_1357 | Thewi_0027 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: tbo:Thebr_1246 membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.622 |
| AEM78779.1 | topA | Thewi_1357 | Thewi_1404 | TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; KEGG: tbo:Thebr_1246 membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.683 |
| AEM79494.1 | AEM77543.1 | Thewi_2144 | Thewi_0027 | KEGG: tbo:Thebr_0487 DNA polymerase LigD, ligase domain-containing protein; TIGRFAM: DNA polymerase LigD, ligase region; PFAM: ATP dependent DNA ligase, central. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.724 |
| atpE | AEM77543.1 | Thewi_0746 | Thewi_0027 | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.494 |
| ffh | AEM77543.1 | Thewi_1417 | Thewi_0027 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.514 |
| ffh | lepA | Thewi_1417 | Thewi_1039 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.469 |
| ffh | rimM | Thewi_1417 | Thewi_1414 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.808 |
| ffh | topA | Thewi_1417 | Thewi_1404 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.692 |
| lepA | AEM77543.1 | Thewi_1039 | Thewi_0027 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | KEGG: tbo:Thebr_0028 signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region. | 0.715 |