STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77574.1TIGRFAM: HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; KEGG: tbo:Thebr_2241 metal dependent phosphohydrolase; SMART: Metal-dependent phosphohydrolase, HD region. (390 aa)    
Predicted Functional Partners:
AEM79731.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; KEGG: tte:TTE1052 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate cyclase, predicted.
 
 0.812
AEM79649.1
Diguanylate cyclase with GAF sensor; TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; GAF; KEGG: tbo:Thebr_0340 diguanylate cyclase; SMART: Diguanylate cyclase, predicted; GAF.
 
 0.793
AEM79712.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: tbo:Thebr_0292 EAL domain-containing protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted.
 
  
 0.792
AEM78162.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold-3; PAS fold; KEGG: tte:TTE1081 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS; PAC motif.
  
 0.661
AEM77575.1
KEGG: tbo:Thebr_2240 hypothetical protein.
       0.633
crcB
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.615
crcB-2
CrcB-like protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.615
AEM79709.1
Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; manually curated; KEGG: tit:Thit_0615 response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS; PFAM: PAS fold; Signal transduction response regulator, receiver region; Diguanylate cyclase, predicted.
   
 0.528
AEM77568.1
Putative PAS/PAC sensor protein; TIGRFAM: PAS; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; HAMP linker domain; PAS fold; KEGG: tbo:Thebr_2247 PAS sensor protein; SMART: Metal-dependent phosphohydrolase, HD region; PAS; HAMP linker domain.
 
   
0.524
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
   0.508
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.