Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEM77579.1TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; KEGG: tbo:Thebr_2236 pseudouridine synthase; SMART: RNA-binding S4. (241 aa)    
Predicted Functional Partners:
AEM79555.1
Exodeoxyribonuclease III Xth; KEGG: tte:TTE2226 exonuclease III; TIGRFAM: Exodeoxyribonuclease III xth; AP endonuclease, family 1; PFAM: Endonuclease/exonuclease/phosphatase.
  
    0.915
cmk
TIGRFAM: Cytidylate kinase; HAMAP: Cytidylate kinase; KEGG: tbo:Thebr_1196 cytidylate kinase; PFAM: Cytidylate kinase region; Shikimate kinase.
 
  
 0.772
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.697
scpB
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
  
 0.602
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   
 0.523
AEM79799.1
TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; KEGG: tit:Thit_2142 small GTP-binding protein; SMART: Ras small GTPase, Ras type.
  
  
 0.448
AEM77580.1
KEGG: tit:Thit_0045 transcriptional regulator, LacI family; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SMART: HTH transcriptional regulator, LacI.
  
    0.421
AEM79137.1
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
 
 
 0.414
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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