Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77595.1PFAM: tRNA methyl transferase-like; KEGG: tbo:Thebr_2218 PP-loop domain-containing protein; Belongs to the TtcA family. (297 aa)    
Predicted Functional Partners:
AEM78003.1
tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
 
  
 0.797
AEM79808.1
PP-loop domain protein; PFAM: PP-loop; KEGG: thx:Thet_1752 PP-loop domain-containing protein; Belongs to the TtcA family.
  
  
 
0.596
AEM77605.1
Sulfur relay protein TusB/DsrH; KEGG: tte:TTE0087 uncharacterized ACR involved in oxidation of intracellular sulfur; TIGRFAM: Sulphur relay, TusB/DsrH; PFAM: Sulphur relay, TusB/DsrH.
     
  0.540
AEM77596.1
KEGG: tbo:Thebr_2217 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit alpha; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region.
       0.509
AEM77598.1
KEGG: tbo:Thebr_2215 phage SPO1 DNA polymerase-like protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like.
       0.473
AEM77597.1
KEGG: tbo:Thebr_2216 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region.
       0.471
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.429
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.420
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
    
 0.411
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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