STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77595.1PFAM: tRNA methyl transferase-like; KEGG: tbo:Thebr_2218 PP-loop domain-containing protein; Belongs to the TtcA family. (297 aa)    
Predicted Functional Partners:
AEM78003.1
tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
 
  
 0.807
AEM79807.1
PFAM: ThiamineS; KEGG: tte:TTE2469 hypothetical protein.
  
 
 0.579
AEM77596.1
KEGG: tbo:Thebr_2217 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit alpha; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region.
       0.510
AEM77598.1
KEGG: tbo:Thebr_2215 phage SPO1 DNA polymerase-like protein; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like.
       0.474
AEM77597.1
KEGG: tbo:Thebr_2216 hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region.
       0.473
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.429
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.420
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (36%) [HD]