Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77599.1SirA-like domain-containing protein; PFAM: SirA-like; KEGG: tte:TTE0081 transcriptional regulator; Belongs to the sulfur carrier protein TusA family. (72 aa)    
Predicted Functional Partners:
AEM79025.1
PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: tbo:Thebr_0819 class V aminotransferase.
   
 0.970
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.970
AEM77602.1
PFAM: Protein of unknown function DUF395, YeeE/YedE; KEGG: tte:TTE0084 transporter components.
 
  
 0.900
AEM77600.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: tte:TTE0082 transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
   
 0.848
AEM77603.1
PFAM: Sulphur relay, DsrE-like protein; KEGG: tte:TTE0085 uncharacterized ACR involved in intracellular sulfur reduction.
 
  
 0.829
AEM77601.1
SirA-like domain-containing protein; PFAM: SirA-like; KEGG: tte:TTE0083 transcriptional regulator; Belongs to the sulfur carrier protein TusA family.
 
    
0.558
AEM78430.1
KEGG: tpd:Teth39_1436 hypothetical protein.
  
     0.538
AEM77604.1
KEGG: tte:TTE0086 hypothetical protein.
     
 0.456
AEM77605.1
Sulfur relay protein TusB/DsrH; KEGG: tte:TTE0087 uncharacterized ACR involved in oxidation of intracellular sulfur; TIGRFAM: Sulphur relay, TusB/DsrH; PFAM: Sulphur relay, TusB/DsrH.
     
 0.442
sigI
RNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.
 
     0.434
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.