Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77629.1KEGG: tbo:Thebr_2185 metal dependent phosphohydrolase; TIGRFAM: HDIG; PFAM: Polynucleotide adenylyltransferase region; Metal-dependent phosphohydrolase, HD region, subdomain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (467 aa)    
Predicted Functional Partners:
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
  
 0.764
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.760
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.760
AEM79630.1
PFAM: Lecithin:cholesterol acyltransferase; KEGG: tbo:Thebr_0357 PGAP1 family protein.
 
     0.604
AEM77628.1
PFAM: Nucleoside recognition; KEGG: tbo:Thebr_2186 nucleoside recognition domain-containing protein.
       0.568
AEM77627.1
PFAM: Nucleoside recognition; KEGG: thx:Thet_0098 nucleoside recognition domain-containing protein.
       0.564
polA
5'-3' exonuclease, resolvase-like domain-containing protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.562
AEM78548.1
LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; KEGG: cob:COB47_0277 LmbE family protein.
  
  
 0.529
AEM79391.1
LmbE family protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; KEGG: tbo:Thebr_0541 LmbE family protein.
  
  
 0.529
AEM79038.1
KEGG: tbo:Thebr_0806 hypothetical protein.
  
     0.516
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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