Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77633.1PFAM: 3D; G5; Protein of unknown function DUF348; KEGG: tbo:Thebr_2182 3D domain-containing protein. (343 aa)    
Predicted Functional Partners:
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.912
AEM77632.1
KEGG: tbo:Thebr_2183 hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; PFAM: Deoxyribonuclease, TatD-related.
     
 0.786
AEM77635.1
KEGG: tbo:Thebr_2180 hypothetical protein.
 
     0.711
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.665
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.658
AEM79004.1
PFAM: Protein of unknown function DUF881, bacterial; KEGG: tbo:Thebr_0838 hypothetical protein.
 
     0.613
AEM77776.1
PFAM: Protein of unknown function DUF881, bacterial; KEGG: tbo:Thebr_2048 hypothetical protein.
 
     0.603
AEM79003.1
PFAM: Protein of unknown function DUF1290; KEGG: tbo:Thebr_0839 hypothetical protein.
  
     0.575
AEM79928.1
KEGG: tte:TTE2615 subtilisin-like serine protease; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Protease-associated PA; Peptidase S8A, DUF1034 C-terminal; Bacterial Ig-like, group 2; S-layer homology region; SMART: Bacterial Ig-like, group 2; Belongs to the peptidase S8 family.
  
  
 0.564
AEM78875.1
KEGG: tbo:Thebr_1342 serine/threonine-protein kinase-like domain-containing protein; PFAM: Serine/threonine-protein kinase-like domain; PASTA; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA.
  
   
 0.533
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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