Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM77636.1KEGG: tbo:Thebr_2179 hypothetical protein. (78 aa)    
Predicted Functional Partners:
AEM79644.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 
 0.853
AEM79359.1
KEGG: tbo:Thebr_0569 hypothetical protein.
  
     0.763
AEM79485.1
Manually curated; PFAM: Phosphotransferase system, fructose subfamily IIA component.
  
 
 0.749
AEM79791.1
KEGG: tbo:Thebr_0260 hypothetical protein.
  
     0.679
AEM77989.1
KEGG: tbo:Thebr_1870 PTS system, N-acetylglucosamine-specific IIBC subunit; TIGRFAM: Phosphotransferase system, N-acetylglucosamine-specific IIBC component; Phosphotransferase system, glucose-like IIB component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site.
  
  
 0.619
AEM79177.1
KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region.
  
  
 0.607
AEM79330.1
Transcriptional regulator, CdaR; KEGG: tbo:Thebr_0577 helix-turn-helix fis-type.
  
     0.602
AEM79312.1
PFAM: Protein of unknown function DUF624; KEGG: thx:Thet_1851 hypothetical protein.
  
     0.601
AEM78804.1
TIGRFAM: Flagellar biosynthesis protein, FliO; KEGG: tbo:Thebr_1271 flagellar biosynthetic protein FliO.
  
     0.578
AEM79648.1
PTS modulated transcriptional regulator, MtlR family; PFAM: PRD; Helix-turn-helix, type 11; Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; KEGG: tbo:Thebr_0341 protein-N(pi)-phosphohistidine--sugar phosphotransferase.
   
 
 0.543
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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