Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77640.1ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (370 aa)    
Predicted Functional Partners:
AEM78408.1
PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Sucraseferredoxin-like; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tbo:Thebr_1492 NADH dehydrogenase (quinone).
  
 
 0.860
AEM79231.1
PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: tmt:Tmath_1662 dinitrogenase iron-molybdenum cofactor biosynthesis protein.
  
 0.646
sigI
RNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily.
       0.557
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
   0.531
AEM78291.1
PFAM: Lipopolysaccharide biosynthesis; KEGG: thx:Thet_0698 lipopolysaccharide biosynthesis protein.
  
 
 0.530
AEM77637.1
S-layer domain-containing protein; PFAM: S-layer homology region; KEGG: tit:Thit_0105 S-layer domain protein.
     
 0.478
AEM77638.1
KEGG: tmt:Tmath_0163 hypothetical protein.
       0.474
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
     
 0.461
AEM78931.1
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: thx:Thet_1075 peroxiredoxin.
  
  
 0.423
miaB
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
  
 0.406
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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