STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)    
Predicted Functional Partners:
AEM77651.1
Cobalamin synthesis protein P47K; KEGG: tit:Thit_1610 hydrogenase accessory protein HypB; manually curated; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
 
 
 0.991
AEM77652.1
KEGG: tmt:Tmath_1600 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
   
 0.974
AEM77654.1
KEGG: tte:TTE0133 hydrogenase maturation factor; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
  
 0.973
AEM77653.1
KEGG: tit:Thit_1608 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
  
 0.971
AEM77655.1
KEGG: tit:Thit_1606 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein.
 
  
 0.960
AEM77648.1
NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit; KEGG: tte:TTE0127 NADH:ubiquinone oxidoreductase 49 kD subunit 7.
 
 
 0.897
AEM77644.1
NADH/Ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; KEGG: tmt:Tmath_1608 NADH/ubiquinone/plastoquinone (complex I).
     
 0.895
AEM77646.1
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: tit:Thit_1615 NADH ubiquinone oxidoreductase 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
  
  
 0.854
AEM77649.1
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tmt:Tmath_1603 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.839
AEM77647.1
PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; KEGG: tmt:Tmath_1605 NADH dehydrogenase (ubiquinone) 30 kDa subunit.
 
    0.820
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.