Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77655.1KEGG: tit:Thit_1606 hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. (329 aa)    
Predicted Functional Partners:
AEM77654.1
KEGG: tte:TTE0133 hydrogenase maturation factor; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
 
 0.996
AEM77652.1
KEGG: tmt:Tmath_1600 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
 
 
 0.994
AEM77653.1
KEGG: tit:Thit_1608 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
 
 0.990
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.966
AEM77651.1
Cobalamin synthesis protein P47K; KEGG: tit:Thit_1610 hydrogenase accessory protein HypB; manually curated; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
 
  
 0.963
AEM77649.1
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: tmt:Tmath_1603 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.769
AEM77646.1
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: tit:Thit_1615 NADH ubiquinone oxidoreductase 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
     
 0.763
AEM77648.1
NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit; KEGG: tte:TTE0127 NADH:ubiquinone oxidoreductase 49 kD subunit 7.
     
 0.756
AEM77645.1
PFAM: NADH:ubiquinone oxidoreductase, subunit 1; KEGG: tte:TTE0124 NADH:ubiquinone oxidoreductase subunit 1 (chain H).
     
 0.748
AEM77647.1
PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; KEGG: tmt:Tmath_1605 NADH dehydrogenase (ubiquinone) 30 kDa subunit.
       0.741
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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