Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AEM77684.1TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: tbo:Thebr_2141 sporulation transcriptional regulator SpoIIID. (86 aa)    
Predicted Functional Partners:
AEM78659.1
KEGG: thx:Thet_1374 stage III sporulation protein AE; TIGRFAM: Sporulation stage III, protein AE; PFAM: Sporulation stage III, protein AE.
  
    0.946
AEM78977.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.882
AEM79894.1
Stage V sporulation protein T; KEGG: tmt:Tmath_2137 transcriptional regulator, AbrB family; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted.
  
  
 0.874
AEM79883.1
KEGG: thx:Thet_2320 stage II sporulation protein R; TIGRFAM: Sporulation stage II, protein R; PFAM: Sporulation stage II, protein R.
  
   
 0.866
AEM78655.1
KEGG: tbo:Thebr_1115 stage III sporulation protein AA; TIGRFAM: Sporulation stage III, protein AA; SMART: ATPase, AAA+ type, core.
  
   
 0.862
AEM78676.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.858
AEM79000.1
Hypothetical protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.855
AEM78657.1
KEGG: tbo:Thebr_1117 stage III sporulation protein AC; TIGRFAM: Sporulation stage III, protein AC; PFAM: Sporulation stage III, protein AC.
  
  
 0.854
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.852
AEM79792.1
KEGG: tbo:Thebr_0259 sporulation protein YabP; TIGRFAM: Sporulation protein YabP; PFAM: Sporulation protein YabP.
  
   
 0.849
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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