STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEM77691.1PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: thx:Thet_0151 4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein. (372 aa)    
Predicted Functional Partners:
AEM78409.1
KEGG: tbo:Thebr_1491 hydrogenase, Fe-only; TIGRFAM: Iron hydrogenase, subset; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Iron hydrogenase, small subunit-like.
  
 
 0.916
murJ
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.716
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
       0.694
AEM78405.1
PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; KEGG: tbo:Thebr_1495 NADH dehydrogenase (ubiquinone) 24 kDa subunit.
  
 
 0.592
AEM79843.1
KEGG: elm:ELI_1213 NADH dehydrogenase subunit E.
  
 
 0.592
AEM77688.1
PFAM: Flagellar protein FlgJ, N-terminal; KEGG: tbo:Thebr_2137 flagellar protein FlgJ-like protein.
 
     0.533
AEM77692.1
KEGG: tit:Thit_0149 hypothetical protein.
       0.520
AEM77693.1
KEGG: thx:Thet_0153 hypothetical protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; PFAM: Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.471
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
    0.464
AEM77687.1
KEGG: tbo:Thebr_2138 flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-body rod FlgG; Fagellar hook-basal body protein, FlgE/F/G; Flagellar basal-body rod FlgF; PFAM: Protein of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal.
       0.429
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.