Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM77699.1PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; KEGG: clj:CLJU_c11560 zinc-containing alcohol dehydrogenase. (347 aa)    
Predicted Functional Partners:
AEM79242.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: thx:Thet_1794 PfkB domain-containing protein.
  
 
 0.909
xylA
TIGRFAM: Xylose isomerase, bacterial type; HAMAP: Xylose isomerase; KEGG: tbo:Thebr_2104 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; Belongs to the xylose isomerase family.
     
 0.905
AEM79647.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; KEGG: tbo:Thebr_0342 PTS system, fructose subfamily, IIA subunit; TIGRFAM: Phosphotransferase system, IIA component fructose subfamily; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2.
  
 
  0.903
AEM77723.1
PFAM: Xylose isomerase, TIM barrel domain; KEGG: rxy:Rxyl_0401 xylose isomerase-like protein.
     
  0.900
AEM79910.1
KEGG: tbo:Thebr_0159 PTS system, fructose subfamily, IIC subunit; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, fructose-specific IIB subunit; PFAM: Phosphotransferase system, fructose-specific IIB subunit; Phosphotransferase system, EIIC.
     
  0.900
AEM77700.1
KEGG: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: KDPG/KHG aldolase; PFAM: KDPG/KHG aldolase.
     
 0.680
AEM79698.1
PFAM: Aminotransferase, class I/II; KEGG: tte:TTE2406 7-keto-8-aminopelargonate synthetase and related enzyme.
 
  
 0.543
AEM77702.1
PFAM: Phosphotransferase system, galactitol-specific IIC component; KEGG: tte:TTE0183 hypothetical protein.
  
 0.497
AEM79860.1
PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase; KEGG: thx:Thet_2299 iron-containing alcohol dehydrogenase.
  
 
 0.494
AEM77965.1
KEGG: tbo:Thebr_1890 pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
     
 0.482
Your Current Organism:
Thermoanaerobacter wiegelii
NCBI taxonomy Id: 697303
Other names: T. wiegelii Rt8.B1, Thermoanaerobacter wiegelii Rt8.B1, Thermoanaerobacter wiegelii str. Rt8.B1, Thermoanaerobacter wiegelii strain Rt8.B1
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